| Title | Developer | Publisher(s) | Exclus. | Japan | Europe | North America |
|---|---|---|---|---|---|---|
| Race Driver : Create & Race[159] | Firebrand Games | Codemasters | Yes | |||
| Racing Gears 2[160] | Orbital | Orbital Media, Incorporated | ||||
| Rainbow Islands Revolution[161] | Taito | JP Taito EU Rising Star Games NA Codemasters | No | |||
| Rally DS[162] | Spike | Spike | Yes | |||
| Ratatouille[8] | Heavy Iron Studios | THQ | No | |||
| Rayman DS[10] | Ubisoft Montreal | Ubisoft | Yes | |||
| Rayman Raving Rabbids[10] | Ubisoft Bulgaria | Ubisoft AU Ubisoft Montpellier | No | |||
| Rayman Raving Rabbids 2[10] | Ubisoft Bulgaria | Ubisoft AU Ubisoft Montpellier | No | |||
| Real Time Conflict: Shogun Empires[163] | Box Clever Interactive | Namco | ||||
| Recipe Collection[164] | Nintendo | Nintendo | ||||
| Resident Evil: Deadly Silence[6] | Capcom | Capcom AU Nintendo | No | |||
| Retro Atari Classics[165] | Taniko | Atari | ||||
| ReWind[166] | Two Tribes | TBA | ||||
| Ridge Racer DS[167] | Nintendo | Namco AU Nintendo | Yes | |||
| Robots[168] | Amaze | VU Games | ||||
| Rhythm n' Notes: Improve Your Music Skills[169] | Success | Agetec Inc. | Yes | |||
| Romance relation the Three Kingdoms[170] | Koei | Koei | Yes | |||
| The Rub Rabbits![13] | Sonic Team | Sega | Yes | |||
| Rune Factory: A Fantasy Harvest Moon[171] | Neverland | Marvelous Interactive NA Natsume | Yes | |||
| Rune Factory 2 | Neverland | Marvelous Interactive (Eur) Ubisoft | Yes |